Tamsulin Capsules Uses Side-Effects Dose Contraindication OverDose In Urdu
Tamsulosin is used by males to treat indications
of an increased prostate ( benign prostatic hyperplasia(also known as BPH).
It doesn’t shrink the prostate size. prostate but works through relaxing muscles
of the prostate and in the bladder. This can help relieve the signs of BPH such
as difficulty getting the urine flowing and a weak flow and the requirement to
urinate frequently or often (including at night, especially in the night of the middle).
Tamsulosin is part of a class of medications known as alpha-blockers.
Avoid using this drug in order to manage hypertension.
Table of Contents
Tamsulin Capsules Uses
(Tamsulosin HCl) capsules are recommended for the
treatment of the symptoms and signs of benign prostatic
hyperplasia (BPH).
DOSAGE AND ADMINISTRATION
TAMSOLIN (Tamsulosin HCl) capsules of 0.4mg daily
suggested as the dose for treatment of symptoms.
signs of BPH. It is recommended to administer it around
half-hour after the same breakfast each day.
In the case of patients who fail to show any response to the 0.4mg dose, they should wait until the next
between two and four weeks of dosing, and the dosage of TAMSOLIN (Tamsulosin
The HCl) capsules may be increased up to 0.8mg each day. If
TAMSOLIN (Tamsulosin HCl) capsules administration is
The discontinuation or interruption of the treatment for several days with either 0.4mg
If you are taking 0.8mg or 0.8mg dosage, treatment must be restarted with or 0.8mg dose. 0.4mg
A daily dose of once.
Tamsulin Side-effects
- The adverse reactions listed below have been reported in the
Use of tamsulosin HCl
The whole body: - Asthenia,
- headache,
- infection
- back pain,
- chest discomfort.
Nervous System:
- Insomnia,
- somnolence,
- dizziness, and a
- decrease in the amount of libido.
Respiratory System:
- Rhinitis,
- pharyngitis and increased cough sinusitis.
Digestive System:
- Diarrhea,
- nausea,
- tooth disorder.
Urinogenital System:
- Abnormal ejaculation
- Special Senses:
- Vision blurred
Tamsulin 0.4 Capsules Contraindications
Tamsulosin HCl is not recommended for patients with hypersensitivity to Tamsulosin HCl
or any other component that is in this product. If you have a previous history of hypotension orthostatic.
Also, taking other alpha-adrenergic blocking agents. If you suffer from severe liver insufficiency.
Tamsulosin HCl should not be recommended to be used in – Women.
The children’s population.
AVOIDANCES
Similar to other alpha1-blockers blood pressure
may occur in a few cases when treatment with tamsulosin due to which, in very rare instances
syncope could occur.
When the first symptoms or symptoms of hypotension are orthostatic
(dizziness and weakness) the patient must rest or lie down until the symptoms go away.
Prior to treatment using tamsulosin HCl the patient must be examined to rule out other
medical conditions that can cause similar symptoms to benign prostate hyperplasia.
A digital rectal exam and, if needed testing for prostate-specific antigen (PSA) must
be conducted prior to treatment, and every few months thereafter. Patients with
end-stage renal diseases (creatinine clearance <10mL/min/1.73m2 ) must be treated
cautiously as they are not studied.
Patients must be aware of
the possibility of priapism in the course of treatment with tamsulosin or other
similar medicines. Patients are advised about the possibility of this reaction.
It is rare, however, if not reported to medical attention, it could cause
permanent Erectile impairment (impotence). In-operative
Floppy Iris Syndrome (IFIS) was observed during cataract surgery
in a few patients who are taking or have previously received treatment with alpha1 antagonists of the adrenoceptor.
Drug Interactions:
The pharmacokinetic interaction between cimetidine HCl and tamsulosin was studied.
The results show significant changes in tamsulosin’s clearance (26 percent decrease) in addition to AUC (44 percent increase).
Thus, tamsulosin capsules containing HCl must be avoided in conjunction with
cimetidine especially when doses are greater than 0.4mg.
It is recommended to exercise caution when
taking warfarin and tamsulosin HCl.
Tamsulosin HCl is to be taken with caution when combined with strong
or moderate inhibitors for CYP2D6 (e.g. the aspirin) and CYP3A4 (e.g. ketoconazole)
particularly when doses are that exceed 0.4mg.
Overdose
A sudden overdose of 5 mg
Tamsulosin HCl was documented.
Hypotension acute (systolic blood pressure of 70mmHg),
as well as vomiting
and diarrhea,
were reported and treated with fluid replacement,
and the patient was discharged on the same day.
If hypotension is acute due to overdosage, cardio-vascular support must be provided and continued.
The blood pressure could be restored as well as heart rates
returned to normal levels by lying the patient down.
If this is not enough, increase the volume of blood and,
if needed, vasopressors may be given. The function of the
kidney should be assessed and other general supportive measures