Spaslar P Syrup Uses Side-effects Dose In Urdu
(Hyoscine butyl bromide)
Every 5 ml of Spasler p syrup contains:
Hyoscine butyl bromide (B.P specs)…5mg.

Spaslar-P Syrup Uses 

SPASLER- P can be used for the short term treatment of:
  1. colics due to renal and biliary calculi.
  2. Acute pain due to spasm of the bile duct, urinary passage, or gastrointestinal tract.
  3. Spastic conditions of the female genital system.
  4. pancreatitis.
  5. the pain of uncertain origin in the abdominal region.

Spaslar-P Syrup Dose

1 teaspoonful 3 times daily
Children 1-6 years:
1- 2 teaspoonfuls 3- 5 times daily
Children over 6 years adult:
2 teaspoonfuls 3- 5 times daily or as directed by the doctor.


Hyoscine butyl bromide has been associated with clinical exacerbations of porphyria and is considered unsafe in porphyric patients. It is also recommended that concurrent use of alcohol should be avoided.
Hyoscine butyl bromide is contraindicated in patients with prostatic enlargement, in whom it may lead to urinary retention, and in those with paralytic ileus or pyloric stenosis. In patients with ulcerative colitis, its use may lead to ileus or megacolon and its effects on the lower esophageal sphincter may exacerbate reflux. Hyoscine butyl bromide should not be given to patients with myasthenia gravis unless it is given to reduce the adverse muscarinic effects of an anticholinesterase agent. It should not be given to patients with closed-angle or narrow-angle glaucoma.
Hyoscine butyl bromide is contraindicated in patients who have a history of Hypersensitivity to any of its components.

Spaslar-P Syrup Side-effects

The peripheral side effects of Hyoscine butyl bromide include dryness of the mouth with difficulty in swallowing and talking, thirst, reduced bronchial, secretions, dilatation of pupils (mydriasis) with loss of accommodation and photophobia, flushing, and dryness of the skin, transient bradycardia followed by tachycardia, with palpitations and arrhythmias and difficulty in maturation as well as a reduction in the tone and motility of gastrointestinal tract leading to constipation.
Hyoscine butyl bromide produces central depression at therapeutic doses and symptoms include drowsiness & fatigue.
Occasionally vomiting may also occur. Since it may affect vision therefore caution should be taken while driving or operating machinery. Toxic doses of Hyoscine butyl bromide cause tachycardia, rapid respiration, and hyperpyrexia.
Spaslar P Syrup Hyoscine butyl bromide should be used with caution in conditions characterized by tachycardia such as thyrotoxicosis, heart failure, and cardiac surgery, where it may further accelerate the heart rate. Care is required in patients with acute myocardial infarction as ischemia and infarction may be made worse. It should be given with care to patients with hypertension caution has been advised in patients with impaired metabolic. Liver or kidney function as adverse CNS effects have been stated to be more likely in these patients. It is generally advisable to be cautious in giving Hyoscine butyl bromide to any patient with diarrhea.
Due to the risk of provoking hyperpyrexia, Hyoscine butyl bromide should not be given to patients especially Children, when the ambient temperature is high. It should also be used cautiously in patients with fever.
The safety of Hyoscine butyl bromide during pregnancy has not yet been established. The usual precautions regarding the use of drugs at this time. Especially during the first trimester, should be observed. Safety during lactation has not yet been established.
Hyoscine butyl bromide should not be used concurrently with CNS depressants. Its effects may be enhanced by the concomitant administration of other drugs with antimuscarinic properties such as amantadine, some antihistamines, butyrophenones and phenothiazines, and tricyclic antidepressants.

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