Calamox Syrup 156.25mg/ml Uses Side-effects Dose In Urdu
Calamox Syrup Dose
Dry suspension 156.25mg/ml:
When reconstituted as directed,
Each 5ml contains:
125mg Amoxycillin as Amoxycillin trihydrate U.S.P and 31.25mg clavulanic acid as the potassium salt.
Dry suspension 312.5mg/5ml (DS):
When reconstituted as directed,
Each 5ml contains:
250mg Amoxycillin as Amoxycillin trihydrate U.S.P and 31.25mg clavulanic acid as the potassium salt.

Calamox Syrup 156.25 Uses

Calamox Syrup 156.25mg/ml Uses for the treatment of common bacterial infection where antibiotics therapy is indicated,  including upper Respiratory tract infections e.g sinusitis,  tonsillitis,  otitis media. Lower Respiratory tract infections e.g acute and chronic bronchitis,  lobar and bronchopneumonia, emphysema, lung abscess skin and soft tissue infection e.g boils, abscess, cellulitis,  wound infections,  intra-abdominal sepsis.  Genito-Urinary Tract infections,  e.g cystitis,  urethritis,  pyelonephritis,  septic peripheral sepsis, pelvic infection,  chancroid, gonorrhea.  Other infections e.g osteomyelitis,  Septicaemia,  peritonitis,  post-operative infections. CALAMOX is also indicated for prophylaxis against infection which may be associated with major surgical procedures involving gastrointestinal,  pelvic,  head and neck,  cardiac,  renal,  biliary tract, and joint replacement surgery.

Calamox Syrup 156.25 Dose

The usual dosage for the treatment of infection.
Mild-Moderate infections.  One CALAMOX 375mg tablet three times a day OR one CALAMOX 625mg tablet two times a day.
Severe infections: one called 625mg tablet three times a day OR one CALAMOX 1G tablet two times a day.  Therapy can be started parenteral and continued with an oral preparation.
The usual recommended daily dosage Calamox Syrup 156.25mg is 25mg/kg day in divided doses every eight hours.  The table below gives the guidance for Children.
25mg/kg day for example a 7.5 kg child would require 2 ml CALAMOX 156.25 mg syrup three times a day.
1-6 YEARS (10-18 KG)
5ml CALAMOX 156.25 mg suspension three times a day.
OVER 6 YEARS (10-40 kg )
5ml CALAMOX 312.5mg DS suspension three times a day.
In more severe infections the dosage may be increased up to 50mg/kg day in divided doses every eight hours.  Each 25mg CALAMOX provides 20mg Amoxycillin and 5mg clavulanic acid.


In mind renal impairment (creatinine clearance > 30ml/min) no change in dosage is required.
In moderate renal impairment
(creatinine clearance 10-30 ml/ min) one 375mg tablet or one 625mg tablet 12 hourly.
In severe renal impairment (creatinine clearance <10ml/min) not more than 375mg 12 hourly.
Dosage with caution; monitor hepatic function at regular intervals Each CALAMOX 375mg, 625mg, 1G tablet contains 0.63 mmol (25mg) of potassium.


CALAMOX is contraindicated in patients with Hypersensitivity to penicillin antibiotics.
Calamox Syrup 156.25mg PRECAUTIONS:
Changes in liver function tests have been observed in some patients receiving CALAMOX.  The clinical significance of these changes is uncertain but CALAMOX should be used within patients with evidence of severe hepatic dysfunction.
In patients with moderate or severe renal impairment, CALAMOX dosage should be adjusted as recommended.
Animal studies have shown no teratogenic effects with the combination of antibiotics in CALAMOX.  The products have been used in human pregnancy in a limited number of cases, with no untoward effect; however, use in pregnancy is not recommended unless considered essential by the physician.  As with all drugs, CALAMOX therapy should be avoided if at all possible.  Especially during the first trimester.  During lactation,  trace quantities of penicillin can be detected in breast milk.

Calamox Syrup 156.25mg SIDE EFFECTS:

Side-effects as with Amoxycillin are common and mainly and transitory in nature.  Diarrhea, pseudomembranous colitis,  indigestion,  nausea,  vomiting, and candidiasis have been particularly low in clinical trials.  An urticarial rash suggests penicillin Hypersensitivity and treatment should be discontinued. The erythematous rash is frequently mild and transient but may be severe when associated with infectious mononucleosis, in which case treatment should be discontinued.  Rare cases of Erythema multiforme, Steven’s Johnson syndrome, and occasional fatal Hypersensitivity reactions (anaphylactic) reactions, and angioneurotic edema have been reported in patients on penicillin therapy.  Hepatitis and cholestatic jaundice have been reported.
The problem of overdosage is unlikely to occur,  if encountered they may be treated symptomatically,
CALAMOX may be removed from the circulation by hemodialysis.

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